Potential Effect of Probiotics on the Modulating of Gut Microbiota in Autism Spectrum Disorders (ASD)

نویسندگان

چکیده

Microbiota is the summation of all microorganisms living in body. The alteration microbiota can lead to chronic diseases, however; colonization with different commensal bacteria correct these deficits. Autism spectrum disorder (ASD) a neurodevelopmental characterized by inadequate communication skills and social withdrawal its etiology uncertain. Typical gastrointestinal (GI) disorders symptoms are associated ASD, prevalence range from 23% 70%. method between brain gut likely microbiota-gut-brain axis. Therefore, intervention studies have been published based on use prebiotics, probiotics fecal transplantation (FMT). In this review, possible correlation ASD demonstrated. Additionally, how microbial (FMT) could modulate might represent potential therapy for patients ASD. Nearly GI functions postulated be affected improved animal studies. ensures transfer several hundred bacterial strains, as opposed probiotic where only certain strains supplemented. For dysbiosis, FMT an interesting new therapeutic choice that considered.

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ژورنال

عنوان ژورنال: Journal of pharmaceutical research international

سال: 2021

ISSN: ['2456-9119']

DOI: https://doi.org/10.9734/jpri/2021/v33i931222